Innate and adaptive immunity: the yin and yang of celiac disease.
نویسندگان
چکیده
Celiac disease is a multigenetic complex inflammatory disorder with an autoimmune component, induced by gluten, a protein found in wheat. It is a unique human disease model to dissect the innate and adaptive immune mechanisms underlying T-cell-mediated tissue destruction and the development of T-cell lymphoma in conditions of chronic T-cell activation.
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عنوان ژورنال:
- Immunological reviews
دوره 206 شماره
صفحات -
تاریخ انتشار 2005